John, Lord Lumley, was born in or about the year 1534. He was the only son of George Lumley of Twing, in the county of Yorkshire, who was executed in 1537 at Tyburn, for high treason. On the death of his grandfather, Lord Lumley, in 1544, John succeeded to the family estates, and in 1547 he was permitted to take the title of Baron Lumley. He matriculated in May 1549, as a fellow-commoner of Queens' College, Cambridge, and was also educated in the court of King Edward VI., whose funeral he attended. On the 29th of September 1553 he was created a Knight of the Bath, and, two days later, was present, together with his wife, at the coronation of Queen Mary;[18] Lady Lumley riding in the third chariot with five other baronesses.

On the accession of Queen Elizabeth, he, with other lords, was appointed to attend her Majesty on her journey from Hatfield to London. In 1559 his father-in-law, the Earl of Arundel, at that time Chancellor of the University of Cambridge, nominated him High Steward of the University. Lord Lumley was sent to the Tower in 1569 on suspicion of being implicated in intrigues to bring about the marriage of his brother-in-law the Duke of Norfolk with Mary, Queen of Scots, and to re-establish the Roman Catholic religion. In the next year he was released, but in October 1571 he was again imprisoned, and he did not obtain his liberty until April 1573, ten months after the execution of the Duke of Norfolk. At a later period he appears to have quite regained the favour of the Queen, for we read that she accepted as a New Year's gift from him in 1584 'a cup of cristall graven and garnished with golde,' and that at the New Year 1587 he presented to her 'a booke, wherein are divers Psalmes in Lattin written, the boards greate, inclosed all over on the outeside with golde enamuld cut-worke, with divers colours and one litle claspe.'[19] In 1580 Lord Lumley lost his father-in-law, who by a deed, dated March 14th, 1566, had conveyed a great part of his estates to Lord Lumley and Jane his eldest daughter, Lord Lumley's wife; and after her decease, Lord Arundel confirmed the same to Lord Lumley by his will, which he made a few months before his death. Among the estates bequeathed were the palace and park of Nonsuch, which in 1590 Lord Lumley conveyed to the Queen in exchange for lands of the yearly value of five hundred and thirty-four pounds. Lord Lumley died on the 11th of April 1609 at his residence on Tower Hill, in the parish of St. Olave, Hart Street, and was buried in Cheam church, in the county of Surrey, where a monument was erected to his memory in the Lumley aisle, which he had built. By his first wife, Jane, who died in 1577, Lord Lumley had three children, who all died in infancy. He had no issue by his second wife, Elizabeth, daughter of John, Lord Darcy of Chiche, who survived him nine years.

Lord Lumley, Bishop Hacket says, 'did pursue Recondite Learning as much as any of his Honourable Rank in those Times, and was the owner of a most precious Library, the search and collection of Mr. Humfry Llyd.'[20] This fine library, which to a great extent was formed by the books bequeathed to him by his father-in-law in 1580, contained many volumes which had evidently been once the property of Archbishop Cranmer, as they bear his name, which is sometimes accompanied by the signature of Lumley, and in other instances by the signatures of both Arundel and Lumley. Lord Lumley also collected a number of portraits.

Lord Lumley made liberal donations of books to the University Library of Cambridge and the Bodleian Library during his lifetime, and also 'bestowed many excellent Pieces printed and manuscript upon Mr. Williams[21] for alliance sake.' After his death in 1609 the remainder of his library, 'which was probably more valuable than any other collection then existing in England, with the exception of that of Sir Robert Cotton,'[22] was purchased by Henry, Prince of Wales. At the Prince's decease in 1612 the books went to augment the old royal library of England, which was given to the nation in 1757 by King George II. A curious and interesting inventory of the 'moveables' found at Lumley Castle after the death of its owner is given in Surtees's History of Durham, vol. ii. pp. 158-163. The goods comprised pictures, sculptures, 'peeces of hangines of arras with golde of the Storie of Troye, Quene Hester, Cipio and Haniball,' etc., hangings of 'gilte leather,' 'Beddes' of gold, silver, and silk, splendid chairs, and velvet and Turkey carpets, and were valued at fourteen hundred and four pounds, seventeen shillings and eightpence, but no mention is made of any books. Most of these treasures were sold by auction at the beginning of the nineteenth century. Among the Royal MSS. preserved in the British Museum is a translation of Erasmus's Institutio Principis Christiani, signed 'Your lordshippes obedient sone, J. Lumley, 1550.' As Lord Lumley's own father was put to death in 1537, this was evidently addressed to his father-in-law, who has written his name Arundel on the first page. Lord Lumley was a member of the old Society of Antiquaries, and in conjunction with Dr. Caldwell[23] he founded a surgery lecture in the Royal College of Physicians, endowing it with forty pounds per annum.

The Lumley family was one of considerable importance and antiquity, and an amusing account is given by Pennant[24] and Hutchinson[25] of a visit paid by King James I. to Lumley Castle on the 13th of April 1603. In the absence of Lord Lumley the King was received by Dr. James, Dean of Durham, 'who expatiated on the pedigree of their noble host, without missing a single ancestor, direct or collateral, from Liulph to Lord Lumley, till the King, wearied with the eternal blazon, interrupted him, "Oh mon, gang na further; let me digest the knowledge I ha gained, for on my saul I did na ken Adam's name was Lumley."'

Lord Lumley's first wife was a very learned lady, and several volumes containing the exercises both of herself and her sister, the Duchess of Norfolk, are preserved among the Royal MSS. in the British Museum, having been handed down with the Lumley books. A quarto volume,[26] upon the first leaf of which is written 'The doinge of my Lady Lumley, dowghter to my L. Therle of Arundell,' contains Latin translations of several of the Orations of Isocrates, and 'The Tragedie of Euripides called Iphigeneia, translated out of Greake into Englisshe.' Among the royal manuscripts is also to be found a beautiful little volume of fourteen vellum leaves,[27] containing copies of moral apophthegms, in Latin, which Sir Nicholas Bacon had inscribed on the walls of his house at Gorhambury. On the first page, above the arms of Lady Lumley, which are splendidly emblazoned, is written in gold capitals, 'Syr · Nicholas · Bacon · Knyghte · to · his · very · good · ladye · the · ladye · Lumley · sendeth · this,' and on the second page this title, 'Sentences printed in the Lorde Kepar's Gallery at Gorhambury: selected by him out of divers authors, and sent to the good ladye Lumley at her desire.' The sentences, which are thirty-seven in number, are inscribed in gold capital letters upon grounds of various colours.

There are three portraits of Lord Lumley at Lumley Castle, and one at Arundel Castle. A fine engraving of another portrait, which was formerly in the Lumley aisle at Cheam, is in Stebbing's edition of Sandford's Genealogical History. There are also engravings of Lord Lumley by Fittler and Thane. Lumley Castle also contains a portrait of Lady Lumley, inscribed 'Jane Fitzalan, daughter to Henry Earle of Arundele, first wife to John Lord Lumley.'[28]