  | Page. | | Geographical distribution of the loco-weed disease and allied conditions | 9 | | Plants associated with the locoed condition | 10 | | Clinical symptoms of locoed animals as described in literature | 12 | | Conditions similar to loco-weed poisoning in other parts of the world | 16 | | Pathological conditions in locoed animals as described on the range | 18 | | Historical sketch of loco investigations from a pharmacological standpoint | 19 | | Notes on various members of the loco-weed family | 35 | | Laboratory experiments—physiological | 36 | | Experiments on rabbits | 36 | | Acute cases | 36 | | Chronic cases | 38 | | Pregnant animals | 42 | | Subcutaneous injections | 43 | | Summary of feeding experiments on rabbits | 44 | | Experiments on sheep | 44 | | Laboratory experiments—chemical | 46 | | Effect of the aqueous extract of ashed loco plants | 49 | | Total ash determinations of loco plants | 54 | | Barium determinations in the ash of loco plants | 55 | | Analysis of soils | 57 | | Feeding experiments with barium salts on animals in the laboratory | 57 | | Barium poisoning in man | 62 | | Pathological lesions in experimental barium poisoning | 65 | | Toxicity of various aqueous extracts of loco plants | 66 | | Theoretical antidote for loco-weed poisoning | 71 | | Action of barium on domestic and farm animals | 72 | | Application of the results of these investigations to the range | 74 | | Conclusions | 75 | | Index | 77 |
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