Title: Abstracts of Papers Read at the First International Eugenics Congress University of London, July, 1912 Author: Various Language: English Character set encoding: ISO-8859-1 E-text prepared by Curtis Weyant, Tom Cosmas, |
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In his paper Professor G. Sergi wishes to show that in man after his morphological characteristics are established there occur no profound variations to change the typical forms which are naturally persistent.
The principal discussion concerns the different forms of the skull which are important as characteristics of race. Professor Sergi distinguishes in the human skull two principal and primordial forms: the dolichomorphic and the brachymorphic are both very ancient, as they are found contemporaneously in European human fossils. Consequently he attacks the idea of the transformation of one form into another. He does not find it demonstrated that the dolichomorphic type is transformed into the brachymorphic, and considers the causes adduced for this supposed transformation insufficient. It is neither the effect of environment of the plains or of the mountains, or the climatic influence of extreme cold, or the increase of volume of the brain supposed to be due to greater cerebral activity owing to a more developed culture, that the form of the skull is transformed into another type. All these suppositions are contrary to facts, because dolichomorphic and brachymorphic skulls are found alike in mountain and plain, in northern and southern regions, among primitive and civilized populations, in fact without any distinction.
The mutations that are believed to be found in the different populations are due to the effect of intermixture and penetration of new demographical elements, and not to the transformation of forms. That is also proved by the crossing of the two different human types from which no intermediary forms are derived: but instead there occurs in the heredity a segregation analagous to that under the Mendelian theory. If this were not so, to-day after many thousands of years of intermixture of the most diverse races, there would be but a single form derived from transformation; the demonstration of the facts proves that this has not occurred.
There is a great persistence in human physical forms, the variability is minimum after the formation of the races, and does not effect the changes of type.
The same fact can be noticed for the external characteristics of man, such as the colour of the skin, the colour and form of the hair, and the colour of the iris. It is solely in the crossings that there can be intermediary formations which have not indefinite heredity, because the segregation of characteristics takes place also in this case.
But the studies and observations on this matter are still incomplete, especially according to the Mendelian theory, and there is need of new and careful observation.
As to the pathological inheritance, there exist facts that confirm it in a general way, but the laws under which this heredity occurs have not been fully verified.
The improvement in stature in many European countries during the past 50 years is generally ascribed simply to improved hygienic and economic conditions, but the question is really very intricate. The presence of different racial elements, social selection with its tendency to draw the well-made into towns, and the falling death-rate, etc., complicate the investigations. In all countries there is a great lack of truly comparable data from earlier years. The British Inter-Departmental Committee on Physical Deterioration, for example, though it collected an enormous amount of material, was unsuccessful in its endeavours to solve the main question. Single cases, e.g., the comparison of factory children with the boys of the York Quaker school (Anthropometric Committee, Brit. Ass. 1883), are certainly of great interest, but how can such cases be taken to represent the average?
Other countries possess a rich source of information in their conscription lists. Thus, in Denmark these lists show an unmistakable increase of 3.7 cm. (11/2 inch) in the average height of the adult Dane during the past 50-60 years. Similar increases are noted from Norway, Sweden and Holland. This increase suggests that there may have been more or less periodic waves of increase and decrease in height, since, on the one hand, we cannot imagine such an increase continuing indefinitely, and on the other, we know that the men of, say, 1000 years ago were quite as tall as they are at present. What are the agencies alternately improving or impairing the racial qualities? First of all, have we sufficiently exact, numerical information regarding the racial qualities?
A critical examination of all available data is very necessary. For example, the weight of new-born children is stated to have increased in England by 59 and 82 grams during the past 20 years, and in Denmark we can point to an increase of 40 grams in 35 years. But when we consider all the possible sources of error, it must be admitted that these statements, and especially the former, require confirmation. The material is not homogenous. Again, it is stated, that the average height of adult women in France has increased by 3 cm. in the last 80 years—but when we read that the total number of measurements in the last period was only 255, we cannot rely very much upon this statement.
On the whole, it may be said, that we have a few cases of definite increase and a goodly number very doubtful. We really need to have the first of the principal recommendations of the Inter-Departmental Committee on Physical Deterioration carried out in all countries, for, the more we subject the available data to critical scrutiny, the more we see the hopelessness of attaining to any real and fruitful conclusions, unless we have an efficient organisation of capable workers, backed by governmental as well as private support.
The Mendelian laws find verification in man. Every race, whether a sub-species or a variety, has an hereditary possession of certain characters; a possession which is completely transmitted to the descendants, in whom is preserved the same germ plasm as in the progenitors.
The researches of C. B. and G. Davenport seem to have proved the recessive character of albinism and its obedience to the Mendelian law. Hurst has presented figures which show that the inheritance of colour in the iris of the human eye obeys Mendelian laws. Davenport has established the order of dominance by the form of hair, which also obeys the Mendelian law.
De Quatrefages, many years before the re-affirmation of Mendel's discoveries, wrote:—
"The union of individuals of different races involves a contest between their two natures—a contest of which the theatre is the field where the new being is organised. Now, this contest does not take place en bloc, so to speak, as has been generally admitted. Each of the characters of the two parents struggles on its own account against the corresponding character (its antagonist, as has just been said). When the hereditary energy is equal on both sides there necessarily ensues a kind of process of which the consequence is the fusion of the maternal and paternal characters in an intermediate character. If the energies are very unequal the hybrid inherits a character borrowed entirely from one of his parents; but this parent, conqueror on one point, may be conquered upon another. Hence, there results with the hybrid a juxtaposition of characters derived from each of the types of which he is the child."
Above all, I have wished to call attention to the so-called laws of dominance, because of their great importance. We may conclude that in the case of man the dominant characters are also the original ones.
The purpose of this paper is to give an account (necessarily abbreviated, and without presentation of complete evidence) of the results of an investigation into the mode of inheritance of fecundity in the domestic fowl, and to point out some of the possible eugenic bearings of these results.
It is shown that while the continued selection, over a period of years, of highly fecund females failed to bring about any change in average fecundity of the strain used, this character must nevertheless be inherited since pedigree lines have been isolated which uniformly breed true to definite degrees of fecundity.
It is further shown that observed variations in actually realized fecundity (number of eggs laid) do not depend upon anatomical differences in respect to the number of visible oÖcytes in the ovary. The differential factor on which the variations in fecundity depend must be primarily physiological.
Fecundity in the fowl is shown to be inherited in strict accord with the following Mendelian plan:—
1. Observed individual variations in fecundity depend essentially upon two separately inherited physiological factors (designated L1, and L2).
2. High fecundity is manifested only when both of these factors are present together in the same individual.
3. Either of these factors when present alone, whether in homozygous or heterozygous form, causes about the same degree of low fecundity to be manifested.
4. One of these factors, namely L2, is sex-limited or sex-correlated in its inheritance, in such way that in gametogenesis any gamete which bears the female sex-determinant F does not bear L2.
5. There is a definite and clear-cut segregation of high fecundity from low fecundity, in the manner set forth above.
From the standpoint of eugenics it is pointed out that these results furnish a new conception of the mode of inheritance of fecundity, and may be helpful in suggesting a method of attacking the same problem for man.
All natural varieties or races of mankind differ, not only by their physical, but also by their mental, characters. There exists, therefore, an "Ethnic Psychology" which, along with "Ethnic Somatology," constitutes the complete Science of Anthropology or the Natural History of Man. This must describe and classify races and populations under a double aspect—physical and psychical.
The psychical characters of races are in part original, and in part acquired through adaptation. These persist in a race as long as such mesological adaptation lasts; they vary with modifications of the conditions of life, including social activities and inter-racial relations.
In mixed unions, amongst different races, there are always some which are more vigorous, biologically and mentally, more fully developed, which impress their characters upon their descendants. For the vitality and well-being of mixed or metamorphic populations a certain amount of difference amongst the parent races is necessary, but too great a difference is injurious to the offspring.
The offspring of mixed unions present in their psychology a mixture, again a combination or fusion of the mental characters of the parent races: sometimes certain psychical characters of a race become the dominant characters.
All ethnic groupings have their destiny marked out by the grade attained in the human psycho-physical hierarchy. Nevertheless, it is necessary that each race or nation, when it knows its contribution to the development of universal civilisation, should contemplate the preservation of its own ethnic type. Differentiation amongst peoples is an indispensable factor in human progress.
The science of eugenics should not look for the realisation of a uniform type of man, but vary its aims and methods according to the natural differentiation of races and nations, taking account of ethnic psychology equally with ethnic somatology.
The humanity of the future will be physically and mentally superior to the existing humanity, but the amelioration of the species ought not to aim at the equality of races and populations. These races and populations ought not to lose their acquisition of particular adaptations to different conditions of existence.
A science of universal or common eugenics should allow a eugenic ethnology to exist, which should indicate and facilitate for each race or nation the defence and propagation of its own physical type and its own mentality. The most vigorous and dominant races will always be those which know how to create and preserve in sexual unions their characteristics of structure and culture.
In this paper the writer has endeavoured to learn what laws, if any, epilepsy follows in its return to successive generations, and the relation it bears to alcoholism, migraine, paralysis, and other symptoms of lack of neural strength.
The data used in the study was analysed according to the Mendelian method which assumes that the inheritance of any character is not from the parents, grandparents, etc., but from the germ plasm out of which every fraternity and its parents and other relatives have arisen. If the soma possesses the trait of the recessive to normality sort, it lacks in its germ plasm the determiner upon which the normal development depends, and this condition is called nulliplex. If the soma possesses the trait of the dominant to normality sort, the determiner was derived from both parents and is double in the germ plasm, or normal, all of the germ cells have the determiner; or else it came from one parent only, is single in the germ plasm, or simplex, and half of the germ cells have and half lack the determiner.
The method of obtaining the data was by means of field workers, who interviewed in their homes the parents, relatives and all others interested in the epileptic patient. These visits have established a friendly feeling toward and an intelligent understanding of the Institution and its work.
The study is based on the data derived from 397 histories, covering 440 matings.
The matings are classified under the six possible types, of nulliplex × nulliplex, nulliplex × simplex, nulliplex × normal, simplex × simplex, simplex × normal, and normal × normal.
Under the first type all those matings where both parents were epileptic, one was epileptic and the other feeble-minded, or both were feeble-minded, are classified. According to Mendel's Law, all of the children should be nulliplex. The data showed all of the children defective.
Under the type nulliplex × simplex, all matings where one parent was epileptic or feeble-minded and the other "tainted," that is, alcoholic, neurotic, migrainous, or showed some mental weakness, are classified. From this type of mating, 50% of the offspring are expected to be nulliplex and 50% simplex. From the matings where one parent was epileptic or feeble-minded and the other alcoholic, there were 61% mentally deficient or nulliplex, the remainder simplex. The figures for the offspring from the other matings showed 47% nulliplex, and 53% simplex.
For the third type, nulliplex by normal, all those matings where one parent was epileptic or feeble-minded and the other reported as mentally normal are classified. From this type of mating, the expectations are that all of the children would be simplex. A study of the ancestors of the normal parents showed these parents simplex rather than normal. The analysis of the offspring showed at least 43% nulliplex, which is a close fitting to the type of mating nulliplex × simplex.
The fourth type of mating is simplex × simplex. Here, all matings where both of the parents were "tainted" are classified. The expectation is that 25% of the offspring would be nulliplex, in reality 35% were found to be mentally deficient.
Simplex × normal is the fifth type of mating considered. The matings where one parent was tainted and the other supposedly normal, are classified here. From a study of their ancestors these normal parents appeared to be simplex, and the classification of the offspring showed more than 25% nulliplex, which is the expectation from simplex × simplex mating.
The sixth type is normal × normal, and the matings where both parents were reported normal is studied under this heading. Here, as before, a study of the ancestors of these normal parents indicates that they are simplex, and not normal. The classification of the children showed a close fitting to the expectation from a simplex × simplex mating.
A special study of the matings where one or both of the parents was migrainous or alcoholic, shows a close relationship between these conditions and epilepsy.
The following conclusions are drawn from the study.
The common types of epileptics lack some element necessary for complete mental development. This is also true of the feeble-minded.
Two epileptic parents produce only defectives. When both parents are either epileptic or feeble-minded their offspring are also mentally defective.
Epilepsy tends in successive generations to form a larger part of the population.
The normal parents of epileptics are not normal but simplex, and have descended from tainted ancestors.
Alcohol may be a cause of defect in that more children of alcoholic parents are defective than where alcoholism is not a factor.
Neurotic and other tainted conditions are closely allied with epilepsy.
In the light of present knowledge, epilepsy, considered by itself, is not a Mendelian factor, but epilepsy and feeble-mindedness are Mendelian factors of the recessive type.
Tainted individuals, as neurotics, alcoholics, criminals, sex offenders, etc., are simplex and normals or simplex and normal in character.
The natural law of heredity holds good whether for the physical characteristics or for those which are biological and moral.
The apparent anomalies which children present in not reproducing the qualities of the parents, and the unlikeness frequently noted among the children of the same family, only serve to reveal the presence of the particular conditions of the parents at the time of begetting which has influenced the offspring.
We have a proof of this law in the anomalies presented by the children of parents who, at the time of begetting, were themselves in anomalous conditions by reason of intoxication or disease.
Among the conditions of parents which are capable of influencing the characteristics of children must be included the changes which their organism undergoes by reason of advancing age.
I propose to study the effects of age on the physical and moral characters of the children. My researches have extended to numerous criminals and insane persons, as well as to scholars of the public schools and other normal persons affected or not with special diseases.
Of my studies on criminals, the result is: that the children of young parents are found in large numbers guilty of offences against property; and this is natural. The first impulse to that is not due to wickedness, which impels them to inflict harm on others, but to love of pleasure, of revel, of idleness—all features of youth, during which period the passions are very active, and no restraint present with which to repress and subjugate them.
Swindlers alone are exceptions to this rule, but swindling is a crime of riper years, according to the dictum of Quetelet.
Among crimes of personal violence, I have found a numerical superiority in the children of aged parents. Assassins, homicides, those who show the completest absence of sentiments of affection and often delusions of persecution more or less pronounced, gave a proportion of children of aged parents far greater than that furnished by all the other categories of delinquents; the proportion is as high for fathers as for mothers of advanced age.
Here, too, we note a certain correlation between the state of discontent, of suspicion, of frigid egoism, which the decline of physical energy tends to arouse in the old, and the absence of affectionate sentiment and a tendency to delusions of persecution which are usual in murderers. Among the insane, moral idiocy in particular, and the degenerative forms in general, appeared more frequently in children of aged parents.
As to schoolboys, I have noticed that the minimum of good conduct and the maximum of better developed intelligence coincides with the possession of youth by both parents.
The age of complete development corresponds to a maximum of good conduct and a minimum of bad conduct, and retains a large proportion of intelligent children.
In the period of decline of both parents, good conduct of children is observed in a smaller proportion than in the preceding period, and high intelligence in a very small proportion.
Among biological qualities I have made observations on longevity; among persons of 70 and 80 whom I have examined there is a large proportion of parents who themselves enjoyed remarkably long lives, which proves the transmissibility from father to son of powers of resistance against the stresses of life.
Among physical qualities I have made note of the fact that from alcoholic or aged parents were descended children in whom degenerative physical characteristics were most frequently apparent, recalling some features of an inferior human type, such as exaggeration of the frontal sinuses, the torus occipitalis, ears with the Darwinian tubercles prominent, the forehead receding, etc. At the same time the ascendants of those who presented typical and anomalous characters, due to morbid influences of various kinds and following on faulty development of the foetus, such as cretinism, congenital goÎtre, nasal deflections, strabismus, plagio-cephaly, hydrocephaly, dental malformation, etc., showed a large number of alcoholics and epileptics.
The explanation of the pernicious consequences to the psycho-physical characters of the children of parents too young or too advanced in age does not present much difficulty.
At the younger period the organism is still in process of formation; the incomplete development of the skeleton, as of all the other organs, continually absorbs a mass of plastic materials necessary to the formation of offspring. So we may consider that the faults of children born of too young parents are due to an incomplete development because of the insufficiency of plastic material.
We must, on the other hand, seek in the conditions which accompany old age for the reason why it has a disastrous influence on the vitality of the germinal elements of the parents and predisposes the descendants to various forms of physical and moral degeneracy.
During this period we have in the tissues, instead of a development and renewal of protoplasm, the tendency to an accumulation of fat; and in the whole organism, chiefly in the tissues of the arterial system, we find the tendency to a deposit in their structure of an amorphous substance which converts the supple elastic canals into rigid tubes; and from this a general slowing up of the organic functions (circulation, oxidation, secretion) results; the blood, not reaching the degree of elaboration which it possessed before, acquires a greater acidity, and cannot by the ordinary excretory channels so quickly get rid of the catabolic products with which it is charged.
By reason of these conditions the organism of older people undergoes a sort of slow and gradual intoxication, which, at the same time as it shows itself in the individual by the gradual languishing of all his functions, influences in a disastrous manner the germs which develop within him, and predisposes them to become beings condemned to degeneracy.
Consequently this cause of degeneracy enters the general category of intoxications.
To the student of genetics, man, like any other animal, is material for working out the manner in which characters, whether physical or mental, are transmitted from one generation to the next. Viewed in this way he must be regarded as unpromising, not only from the small size of his families, the time consumed in their production, and the long period of immaturity, but also because full experimental control is here out of the question. For these reasons man is of interest to the student of genetics, chiefly in so far as he presents problems in heredity which are rarely to be found in other species, and can only be studied at present in man himself. The aim of the Eugenist, on the other hand, is to control human mating in order to obtain the largest proportion of individuals he considers best fitted to the form of society which he affects. It is evident that to do this effectually he must have precise knowledge of the manner in which transmission of characters occurs, and more especially of those with which he particularly wishes to deal. Precise knowledge is at present available in man for relatively few characters; and those characters, such as eye-colour, and certain somewhat rare deformities, are not the kind on which the Eugenist lays great stress. The one instance of eugenic importance that could be brought under immediate control is that of feeble-mindedness. Speaking generally, the available evidence suggests that it is a case of simple Mendelian inheritance. Occasional exceptions occur, but there is every reason to expect that a policy of strict segregation would rapidly bring about the elimination of this character.
There is reason to suppose that many human qualities are more complicated in their transmission, and it is probable that certain phenomena now being studied in plants and animals will throw definite light upon man. Though characters are frequently transmitted on the Mendelian scheme quite independently of one another, there are cases known in which they are linked up more or less completely in the germ cells with the determinant of a particular sex. Sex-limited inheritance of this nature has been carefully worked out in particular cases in Lepidoptera and poultry. As yet there is much to be learnt in this direction, and further progress may be expected to lead eventually to a precise knowledge of the mode of transmission of many human defects, such as colour-blindness and hÆmophilia. It is not unlikely that a similar mode of transmission will be found to hold good for many human characters usually classed as normal.
Another set of phenomena which will probably be found of importance in the heredity of man are those included under the terms "coupling" and "repulsion." Characters, each exhibiting simple Mendelian segregation, may become linked together more or less completely in the process of heredity, or the reverse may occur. Our knowledge of these phenomena is at present almost completely confined to cases in plants, but evidence is beginning to be obtained for their occurrence in animals. It is not unlikely that they will be found to play a considerable part in human heredity. For one of the most noticeable things about man is the frequency with which children resemble one or other parent to the seemingly almost complete exclusion of the other. In view of the mongrelisation of the human race, the frequency of these cases is very remarkable, and can hardly fail to suggest that some sort of coupling between characters plays a large part in human heredity.
Except in very few cases, our knowledge of heredity in man is at present far too slight and too uncertain to base legislation upon. On the other hand, experience derived from plants and animals has shewn that problems of considerable complexity can be unravelled by the experimental method, and the characters concerned brought under control. Though the direct method is hardly feasible in man, much may yet be learnt by collecting accurate pedigrees and comparing them with standard cases worked out in other animals. But it must be clearly recognised that the collection of such pedigrees is an arduous undertaking demanding high critical ability, and only to be carried out satisfactorily by those who have been trained in and are alive to the trend of genetic research.
Sir Francis Galton has entitled Eugenics the new science having for its object the study of the causes subject to social control which can improve or impair the racial qualities of future generations, whether physical or mental.
Eugenics, thus defined, is nothing else but "Education before Procreation," which has been studied in France for a number of years, and which constitutes the first part of child-culture, "a science having for its object the search for information relative to the reproduction, preservation, and improvement of the human species"( [1]).