The Everest Expedition of 1922 had no preconceived programme of scientific investigation, and was first and foremost an attempt to get up the mountain; though, as I had been connected with physiological research for some years, I was naturally anxious to make observations on the effect of altitude on the human frame. These observations were rather subjective, and were unaccompanied by any accurate data—in other words, the reader will be relieved to hear that there are no tables of figures to be reproduced. Barcroft and others were in the course of their Expedition to the Andes, and I knew full well their results would supply more accurate information on the exact process of acclimatisation at high altitudes than anything we could do with our simpler apparatus. We left it to this other Expedition, therefore, to supply the figures, while our observations were exclusively on the practical side; that is to say, we observed the rapidity and effect of acclimatisation, while not investigating exactly how it is brought about. The first effect of altitude, in such moderate degree as we encountered it on the plains of Tibet, was almost 7.For the benefit of the non-medical reader, Cheyne-Stokes breathing is the gradual alternation of shallow and deep respirations: usually about ten shallow breaths are followed by respirations which get gradually deeper; then by three or four really deep ones, which become shallower until the cycle recommences. It was when we began the more serious work on the mountain that we made the most interesting observations on acclimatisation, and proved both its rapidity (which was known before) and its persistence to great heights. Scientists of various schools had, before the start of the Expedition, predicted that acclimatisation would be impossible When Mallory and I arrived at Camp III and established it on the site chosen by the reconnaissance party, our first concern was the preparation of another camp at the North Col. I shall never forget our first ascent up that accursed slope of snow and ice, each step a hardship, every foot a fight; until at last we lay almost exhausted on the top. After a day or two at Camp III below, we went up again to the col, this time with Strutt and Morshead, and I think Norton. The ascent of the col this time was hard work, but not more than that; and after the col had been reached Morshead and I were sufficiently cheerful to explore the way leading up to Everest. A day or two later we again ascended the North Col, and never really noticed more discomfort than was occasioned by breathlessness. Thus, by sojourn and exercise for a week above 20,000 feet, we obtained the physiological equipment necessary for an attempt on the mountain, and at this point some personal experiences may be of interest, though possibly of no great importance. We found that, as we ascended, we fell into an automatic rate of breathing; Mallory preferred to breathe slowly and deeply, while rapid and shallower respirations appealed to me; but we all walked upwards at almost exactly the same rate at any given height. Below the North Col, I took three breaths to a step, while at 26,000 feet I was taking five complete respirations; but as long as I was walking slowly enough I experienced no distress or discomfort. If one hurried for a short distance, one was forced to rest for a few seconds—a rest was imperative, and one felt it were impossible to do without it; but as long as an even pace was kept up, one had no desire to stop, nor to make one’s In view of our experiences it seems justifiable to predict that acclimatisation at 23,000 feet will be sufficient for the attainment of the summit of Mount Everest, if indeed a sojourn at 21,000 feet is insufficient—which is to my mind more than doubtful. The other important practical observation we made is less encouraging: namely, that we all varied in our rate of acclimatisation, and in fact some of our number (especially the older ones among us) actually seemed to deteriorate in condition while staying at a great height. But I think we proved that it is possible to climb to the summit of Everest without the use of oxygen, though the selection of men who are able to do so is very difficult until those heights are actually reached at which acclimatisation becomes established. Personally I felt perfectly well at 27,000 feet, and my condition seemed no different at that height from what it had been at 25,000 feet, or even lower; and I have no doubt there are many people, if only they can be found, who can get to the top of Everest unaided save by their own physiological reaction to a life at 21,000 feet for a few Among subsidiary effects of extreme altitudes, were those upon appetite, temper, and mental condition generally. Most of us will admit a good deal of peevishness and irritability while at a level of 22,000 feet and more; for the altitude undoubtedly makes one lose to some extent one’s mental balance, and the first way in which this appears on the surface is by a ruffling of the temper. In addition, one has a certain lack of determination, and when at a I have mentioned the deleterious effect of altitude on the appetite of some of our older members; but the same was to some extent true of us all. I have the most vivid recollection of distaste for food during our first few days at Camp III, and especially of the way one had almost to push a prune down one’s throat on the way up to the North Col; but with the majority of us this distaste for food (especially for meat and the slowly-digested foods) diminished during our sojourn at great heights, though our appetites never became quite normal until we reached one of the lower camps. Those who had oxygen reported that they had large appetites above the North Col; and there is no doubt that it is the rarefaction of the air that causes this alteration of the appetite. One may perhaps be justified in assuming that the secretion of gastric juice is diminished while air that is poor in oxygen is inhaled, though it is rather hard to understand how this is brought about. Although acclimatisation is not entirely connected with the actual increase in the number of blood corpuscles (as has been proved by Barcroft in 1922), yet this is still recognised as one of the important factors in its production. The chief point still remaining to be mentioned concerns the after-effects of the climbing of Everest; but these varied so much that they give us little or no scientific information. Some of us were tired for twenty-four hours only, some for many days; some were reported to have enlarged hearts, while in some the heart was normal; some were incapacitated by frostbite, though their general physical condition was very probably good. One therefore cannot generalise about after-effects, but as a medical man I felt strongly (by observation on myself and my companions on the Expedition) that if one is to “live to fight another day” and to require the minimum recuperation period after an attempt on the mountain, it is essential during the attempt to keep oneself well within one’s powers. One is tempted to go too hard, and to exert one’s strength to its limits; but it is just the last few ounces of strength which call forth the greatest effort and make the maximum demands on one’s resources; and if these resources are to be used to |