| CHAPTER I. |
| Chemical Introduction. |
| Summary of symptoms exhibited by various poisons: (1) Sudden death—(2) Insensibility—(3) Vomiting—(4) Action on the eye—(5) Convulsions—(6) Chronic poisoning. Alkaloids, chemically and physiologically—Processes for their detection—Necessity for keeping the extracts separate—Dragendorff’s process—Dr. Guy’s sublimation process—Effects on animals—Doubtful value of this test—Preparation and effects of reagents: (1) Mayer’s—(2) Potassium tri-iodide—(3) Sonnenschein’s test—(4) Bismuth—(5) Phosphotungstic acid—(6) Picric acid—(7) Animal charcoal—(8) Platinic chloride—(9) Tannin or Tannic acid—(10) Phospho-antimonic acid—(11) Silico-tungstic acid—(12) Auric, palladium and mercuric chlorides—Ptomaines or cadaveric alkaloids; difficulties raised by their discovery—Principles to be observed in analysing | 1 |
| CHAPTER II. |
| Trials for Poisoning by Prussic Acid | 16 |
| (1) John Tawell (Slough Case), March, 1850. |
| (2) George Ball (Lewes Case), July, 1860. |
| (3) Peter Walker (Egglesham Case), Dec., 1857. |
| CHAPTER III. |
| Hydrocyanic or Prussic Acid. |
| Nature of—Strength of different preparations of, English and foreign—Where found—Tests, preliminary: (1) Odour—(2) Silver—(3) Prussian blue—(4) Sulphur—(5) Guaiacum—(6) Uranium—(7) Picric acid—(8) Cupric sulphate—(9) Cobalt chloride—(10) Mercuric oxide—(11) Peroxide of hydrogen—(12) Mercurous nitrate. Test apparatus—Salts of hydrocyanic acid: (1) Potassium cyanide—(2) Mercuric cyanide—(3) Cyanides of the heavy metals—(4) Double cyanides—(5) Sulphocyanides—Oil of bitter almonds—Antidotes—Fatal dose—Symptoms—Post-mortem appearances—Drops and minims—Period after death at which hydrocyanic acid can be discovered—Formic acid to be tested for—Processes | 55 |
| CHAPTER IV. |
| Trials for Poisoning by Strychnia | 84 |
| (1) William Palmer (Rugeley Case), May, 1856. |
| (2) William Dove (Leeds Case), July, 1856. |
| (3) Silas Barlow (Vauxhall Case), November, 1876. |
| CHAPTER V. |
| Strychnia and Brucia. |
| Contained in St. Ignatius’s bean—False Angostura bark—Nux Vomica, &c.—Properties of strychnia—Facility of detection. Tests: (1) Microscope—(2) Taste—(3) Color test; ditto in other alkaloids, in bile, and in resinous and saccharine matters—(4) Physiological test (Marshall Hall)—(5) Bichromate of potash—(6) Picric acid—(7) Sulphuric acid and sodium nitrite—(8) Mercuric chloride. Preparations of strychnia: Vermin killers—Battle’s, Gibson’s, Miller’s, Marsden’s, Barber’s, Hunter’s, Keating’s—Brucia—Igasuria—Igasuric acid. Doses of strychnia: medicinal, fatal, recovery—Nux vomica. Fatal period for strychnia—Symptoms in man, commencement of symptoms, if given in powder, in solution, in pills. Explanation of symptoms: by hysteria, tetanus, epilepsy, gritty granules on spinal cord—Angina pectoris. Post-mortem appearances—Treatment—Antidotes—Dr. Taylor’s evidence—Ptomaine—Did Cook die from morphia?—Granular preparations at St. Thomas’s Hospital | 276 |
| CHAPTER VI. |
| Trials for Poisoning by Arsenic | 294 |
| (1) Madeline Smith (_Glasgow Case_), June, 1857. |
| (2) Ann Merritt (Clapton Case), March, 1850. |
| CHAPTER VII. |
| Arsenic. |
| The element (arsenicum)—The oxide (white arsenic)—Arsenicum—Arsenicum trioxide. Forms of: (1) Crystalline—(2) Amorphous—Solubility. Uses and occurrences: (1) Steeping, wheat—(2) Preservation of skins—(3) Antiseptics—(4) Glass making—(5) Fur in boilers—(6) Candles—(7) Preservation of wood—(8) Sheep washes—(9) Scheele’s green and emerald green as pigments in sweets (case of Franklin and Randall), wall papers, toys, &c.—(10) Medicinal—(11) For horses—(12) Tooth-stopping—(13) Aniline dyes—(14) Fireworks—(15) Rat and fly poisons (case of Maria Gage)—(16) For cleansing metals—(17) Arsenic eaters—(18) Cosmetics—(19) For bronzing metals—(20) Beer brewed from glucose—(21) American paper collars—(22) Speculum metal—(23) Inhalation for asthma and bronchitis—(24) Mineral waters. Sulphides of Arsenic: (1) Orpiment (case of M. A. Burdock)—(2) Realgar. Arsenic acid—The arsenates—Arsenic trichloride—Arseniuretted hydrogen—Methods of extraction—Tests—Modifications of old processes suggested—Marsh’s test, distinction of results in arsenic and antimony—Reinsch’s test—Doses—Antidotes—Physiological effects—Remarks—Did L’Angelier commit suicide? | 373 |
| CHAPTER VIII. |
| Trials for Poisoning by Antimony | 397 |
| (1) Dr. Pritchard (Glasgow Case), July, 1865. |
| (2) Dr. Smethurst (Richmond Case), August, 1859. |
| (3) Thos. Winslow (Liverpool Case), August, 1860. |
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