GALEN ON THE NATURAL FACULTIES 5 BOOK I I GALeNOU PERI PHYSIKON DYNAMEON A I PREFACEThe text used is (with a few unimportant modifications) that of KÜhn (Vol. II), as edited by Georg Helmreich; Teubner, Leipzig, 1893. The numbers of the pages of KÜhn’s edition are printed at the side of the Greek text, a parallel mark ("") in the line indicating the exact point of division between KÜhn’s pages. Words in the English text which are enclosed in square brackets are supplementary or explanatory; practically all explanations, however, are relegated to the footnotes or introduction. In the footnotes, also, attention is drawn to words which are of particular philological interest from the point of view of modern medicine. I have made the translation directly from the Greek; where passages of special difficulty occurred, I have been able to compare my own version with Linacre’s Latin translation (1523) and the French rendering of Charles Daremberg (1854-56); in this respect I am also peculiarly fortunate in having had the help of Mr. A. W. Pickard Cambridge of Balliol College, Oxford, who most kindly went through the Pg vi proofs and made many valuable suggestions from the point of view of exact scholarship. My best thanks are due to the Editors for their courtesy and for the kindly interest they have taken in the work. I have also gratefully to acknowledge the receipt of much assistance and encouragement from Sir William Osler, Regius Professor of Medicine at Oxford, and from Dr. J. D. Comrie, first lecturer on the History of Medicine at Edinburgh University. Professor D’Arcy W. Thompson of University College, Dundee, and Sir W. T. Thiselton-Dyer, late director of the Royal Botanic Gardens at Kew, have very kindly helped me to identify several animals and plants mentioned by Galen. I cannot conclude without expressing a word of gratitude to my former biological teachers, Professors Patrick Geddes and J. Arthur Thomson. The experience reared on the foundation of their teaching has gone far to help me in interpreting the great medical biologist of Greece. I should be glad to think that the present work might help, however little, to hasten the coming reunion between the “humanities” and modern biological science; their present separation I believe to be against the best interest of both. A. J. B. 22nd Stationary Hospital, Aldershot. CONTENTS
INTRODUCTIONHippocrates The Beginnings Pg x “Be ye therefore wise as serpents and harmless as doves.” The Asclepiea Hippocrates Celsus says: “Hippocrates Cous primus quidem ex omnibus memoria dignis ab studio sapientiae disciplinam hanc separavit.” He means that Hippocrates first gave the physician an independent standing, separating him from the cosmological speculator. Hippocrates confined the medical man to medicine. He did with medical thought what Socrates did with thought in general—he “brought it down from heaven to earth.” His watchword was “Back to Nature!” At the same time, while assigning the physician his post, Hippocrates would not let him regard that post as sacrosanct. He set his face against any Pg xi tendency to mystery-mongering, to exclusiveness, to sacerdotalism. He was, in fact, opposed to the spirit of trade-unionism in medicine. His concern was rather with the physician’s duties than his “rights.” At the dawn of recorded medical history Hippocrates stands for the fundamental and primary importance of seeing clearly—that is of clinical observation. And what he observed was that the human organism, when exposed to certain abnormal conditions—certain stresses—tends to behave in a certain way: that in other words, each “disease” tends to run a certain definite course. To him a disease was essentially a process, one and indivisible, and thus his practical problem was essentially one of prognosis—“what will be the natural course of this disease, if left to itself?” Here he found himself to no small extent in opposition with the teaching of the neighbouring medical school of Cnidus, where a more static view-point laid special emphasis upon the minutiae of diagnosis. Observation taught Hippocrates to place unbounded faith in the recuperative powers of the living organism—in what we sometimes call nowadays the vis medicatrix Naturae. His observation was that even with a very considerable “abnormality” of environmental stress the organism, in the large majority of cases, manages eventually by its own inherent powers to adjust itself to the new conditions. “Merely give Nature a chance,” said the father of medicine in effect, “and most Pg xii diseases will cure themselves.” And accordingly his treatment was mainly directed towards “giving Nature a chance.” His keen sense of the solidarity (or rather, of the constant interplay) between the organism and its environment (the “conditions” to which it is exposed) is instanced in his book, “Airs, Waters, and Places.” As we recognise, in our popular everyday psychology, that “it takes two to make a quarrel,” so Hippocrates recognised that in pathology, it takes two (organism and environment) to make a disease. As an outstanding example of his power of clinical observation we may recall the facies Hippocratica, an accurate study of the countenance of a dying man. His ideals for the profession are embodied in the “Hippocratic oath.” Anatomy. Impressed by this view of the organism as a unity, the Hippocratic school tended in some degree to overlook the importance of its constituent parts. The balance was re-adjusted later on by the labours of the anatomical school of Alexandria, which, under the aegis of the enlightened Ptolemies, arose in the 3rd century B.C. Two prominent exponents of anatomy belonging to this school were Herophilus and Erasistratus, the latter of whom we shall frequently meet with in the following pages (v. p. 95 et seq.). Pg xiii The Empirics. After the death of the Master, the Hippocratic school tended, as so often happens with the best of cultural movements, to show signs itself of diminishing vitality: the letter began to obscure and hamper the spirit. The comparatively small element of theory which existed in the Hippocratic physiology was made the groundwork of a somewhat over-elaborated “system.” Against this tendency on the part of the “Dogmatic” or “Rationalist” school there arose, also at Alexandria, the sect of the Empiricists. “It is not,” they said, “the cause but the cure of diseases that concerns us; not how we digest, but what is digestible.” Greek The introducer of Greek medicine into Rome was Asclepiades (1st century B.C.). A man of forceful personality, and equipped with a fully developed philosophic system of health and disease which commended itself to the Roman savants of the day, he soon attained to the pinnacle of professional success in the Latin capital: he is indeed to all time the type of the fashionable (and somewhat “faddy”) West-end physician. His system was a purely mechanistic one, being based upon Pg xiv the atomic doctrine of Leucippus and Democritus, which had been completed by Epicurus and recently introduced to the Roman public in Lucretius’s great poem “De Rerum Natura.” The disbelief of Asclepiades in the self-maintaining powers of the living organism are exposed and refuted at considerable length by Galen in the volume before us. The Wild as it may seem, this pathological theory of the Methodists contained an element of truth; in various guises it has cropped up once and again at different epochs of medical history; even to-day there are pathologists who tend to describe certain classes of disease in terms of vaso-constriction and vaso-dilatation. The vice of the Methodist teaching was that it looked on a disease too much as something fixed and finite, an independent entity, to be considered entirely apart from its particular setting. The Methodists illustrate for us the tyranny of names. In its defects as in its virtues this school has analogues at the present day; we are all acquainted with the medical man to whom a name (such, let us say, as “tuberculosis,” “gout,” or “intestinal auto-intoxication”) stands for an entity, one and indivisible, to be treated by a definite and unvarying formula. To such an individual the old German saying “Jedermann hat am Ende ein Bischen Tuberkulose” is simply—incomprehensible. Galen. All the medical schools which I have mentioned were still holding their ground in the 2nd century a.d., with more or less popular acceptance, when the great Galen made his entry into the world of Graeco-Roman medicine. Pg xvi His Nature and Nurture. Claudius Galenus was born at Pergamos in Asia Minor in the year 131 a.d. His father was one Nicon, a well-to-do architect of that city. “I had the great good fortune,” says Galen,1 “to have as a father a highly amiable, just, good, and benevolent man. My mother, on the other hand, possessed a very bad temper; she used sometimes to bite her serving-maids, and she was perpetually shouting at my father and quarrelling with him—worse than Xanthippe with Socrates. When, therefore, I compared the excellence of my father’s disposition with the disgraceful passions of my mother, I resolved to embrace and love the former qualities, and to avoid and hate the latter.” Nicon called his son Γαληνός, which means quiet, peaceable, and although the physician eventually turned out to be a man of elevated character, it is possible that his somewhat excessive leaning towards controversy (exemplified in the following pages) may have resulted from the fact that he was never quite able to throw off the worst side of the maternal inheritance. His father, a man well schooled in mathematics and philosophy, saw to it that his son should not lack a liberal education. Pergamos itself was an ancient centre of civilisation, containing, among other culture-institutions, a library only second in importance to that of Alexandria itself; it also contained an Asclepieum. Galen’s training was essentially eclectic: he studied all the chief philosophical systems of the time—Platonic, Aristotelian, Stoic, and Epicurean—and then, at the age of seventeen, entered on a course of medical studies; these he pursued under the best teachers at his own city, and afterwards, during a period of Wanderjahre, at Smyrna, Alexandria, and other leading medical centres. Returning to Pergamos, he received his first professional appointment—that of surgeon to the gladiators. After four years here he was drawn by ambition to Rome, being at that time about thirty-one years of age. At Rome the young Pergamene attained a brilliant reputation both as a practitioner and as a public demonstrator of anatomy; among his patients he finally numbered even the Emperor Marcus Aurelius himself. Medical practice in Rome at this time was at a low ebb, and Galen took no pains to conceal his contempt for the ignorance, charlatanism, and venality of his fellow-practitioners. Eventually, in spite of his social popularity, he raised up such odium against himself in medical circles, that he was forced to flee the city. This he did hurriedly and secretly in the year 168 a.d., when thirty-six years of age. He betook himself to his old home at Pergamos, where he settled down once more to a literary life. His respite was short, however, for within a year he was summoned back to Italy by imperial mandate. Marcus Aurelius was about to undertake an Pg xviii expedition against the Germans, who at that time were threatening the northern frontiers of the Empire, and he was anxious that his consulting physician should accompany him to the front. “Patriotism” in this sense, however, seems to have had no charms for the Pergamene, and he pleaded vigorously to be excused. Eventually, the Emperor gave him permission to remain at home, entrusting to his care the young prince Commodus. Thereafter we know little of Galen’s history, beyond the fact that he now entered upon a period of great literary activity. Probably he died about the end of the century. Subsequent A few words may be devoted to the subsequent history of his writings. Byzantine Arabian Avicenna (Ebn Sina), (10th to 11th century) is the foremost name in Arabian medicine: his “Book of the Canon in Medicine,” when translated into Latin, even overshadowed the authority of Galen himself for some four centuries. Of this work the medical historian Max Neuburger says: “Avicenna, according to his lights, imparted to contemporary medical science the appearance of almost mathematical accuracy, whilst the art of therapeutics, although empiricism did not wholly lack recognition, was deduced as a logical sequence from theoretical (Galenic and Aristotelian) premises.” Introduction Blending with the Scholastic philosophy at the universities of Naples and Montpellier, the teachings of Aristotle and Galen now assumed a position of supreme authority: from their word, in matters Pg xxi scientific and medical, there was no appeal. In reference to this period the Pergamene was referred to in later times as the “Medical Pope of the Middle Ages.” It was of course the logical side of Galenism which chiefly commended it to the mediaeval Schoolmen, as to the essentially speculative Moslems. The Prominent in this “Humanist” movement was the English physician, Thomas Linacre (c. 1460-1524) who, having gained in Italy an extraordinary zeal for the New Learning, devoted the rest of his life, after returning to England, to the promotion of the litterae humaniores, and especially to making Galen accessible to readers of Latin. Thus the “De Naturalibus Facultatibus” appeared in London in Pg xxii 1523, and was preceded and followed by several other translations, all marked by minute accuracy and elegant Latinity. Two new parties now arose in the medical world—the so-called “Greeks” and the more conservative “Arabists.” Paracelsus. But the swing of the pendulum did not cease with the creation of the liberal “Greek” party; the dazzling vision of freedom was to drive some to a yet more anarchical position. Paracelsus, who flourished in the first half of the 16th century, may be taken as typifying this extremist tendency. His one cry was, “Let us away with all authority whatsoever, and get back to Nature!” At his first lecture as professor at the medical school of Basle he symbolically burned the works of Galen and of his chief Arabian exponent, Avicenna. The Vesalius (1514-64), the modern “Father of Anatomy,” for dissecting human bodies, was fiercely assailed by the hosts of orthodoxy, including that stout Galenist, his old teacher Jacques Dubois (Jacobus Sylvius). Vesalius held on his way, however, proving, inter alia, that Galen had been wrong Pg xxiii in saying that the interventricular septum of the heart was permeable (cf. present volume, p. 321). Michael Servetus (1509-53) suggested that the blood, in order to get from the right to the left side of the heart, might have to pass through the lungs. For his heterodox opinions he was burned at the stake. Another 16th-century anatomist, Andrea Cesalpino, is considered by the Italians to have been a discoverer of the circulation of the blood before Harvey; he certainly had a more or less clear idea of the circulation, but, as in the case of the “organic evolutionists before Darwin,” he failed to prove his point by conclusive demonstration. William Modern medicine, based upon a painstaking Pg xxiv research into the details of physiological function, had begun. Back to Galen’s Influence of “Hippocrates,” he says, “was the first known to us of all who have been both physicians and philosophers, in that he was the first to recognise what nature does.” Here is struck the keynote of the teaching of both Hippocrates and Galen; this is shown in the volume before us, which deals with “the natural faculties”—that is with the faculties of this same “Nature” or vital principle referred to in the quotation. “The Galen’s Galen expressed this idea of the unity of the organism by saying that it was governed by a Physis or Nature (ἡ φύσις ἥπερ διοικεῖ τὸ ζῷον), with whose “faculties” or powers it was the province of φυσιολογία (physiology, Nature-lore) to deal. It was because Hippocrates had a clear sense of this principle that Galen called him master. “Greatest,” say the Moslems, “is Allah, and Mohammed is his prophet.” “Greatest,” said Galen, “is the Physis, and Hippocrates is its prophet.” Never did Mohammed more zealously maintain the unity of the Godhead than Hippocrates and Galen the unity of the organism. Pg xxvii Galen’s Setting aside, however, these occasional half-hearted attempts to apply his principle of a φύσις in regions where it has no natural standing, we shall find that in the field of biology Galen moves with an assurance bred of first-hand experience. The The Anatomists. In defence of the universal validity of his principle, Galen also tends to excessive disparagement of morphological factors; witness his objection to the view of the anatomist Erasistratus that the calibre of vessels played a part in determining the secretion of fluids (p. 123), that digestion was caused by the mechanical action of the stomach walls (p. 243), and dropsy by induration of the liver (p. 171). Characteristics As a type of characteristically vital action we may take nutrition, in which occurs a phenomenon Pg xxix which Galen calls active motion (δραστικὴ κίνησις) or, more technically, alteration (ἀλλοίωσις). This active type of motion cannot be adequately stated in terms of the passive movements (groupings and re-groupings) of its constituent parts according to certain empirical “laws.” Alteration involves self-movement, a self-determination of the organism or organic part. Galen does not attempt to explain this fundamental characteristic of alteration any further; he contents himself with referring his opponents to Aristotle’s work on the “Complete Alteration of Substance” (p. 9). The most important characteristic of the Physis or Nature is its τέχνη—its artistic creativeness. In other words, the living organism is a creative artist. This feature may be observed typically in its primary functions of growth and nutrition; these are dependent on the characteristic faculties or powers, by virtue of which each part draws to itself what is proper or appropriate to it (το οἰκεῖον) and rejects what is foreign (το ἀλλότριον), thereafter appropriating or assimilating the attracted material; this assimilation is an example of the alteration (or qualitative change) already alluded to; thus the food eaten is “altered” into the various tissues of the body, each of these having been provided by “Nature” with its own specific faculties of attraction and repulsion. The Three Categories. Any of the operations of the living part may be looked on in three ways, either (a) as a δύναμις, Pg xxx faculty, potentiality; (b) as an ἐνέργεια, which is this δύναμις in operation; or (c) as an ἔργον, the product or effect of the ἐνέργεια.3 Pg xxxi Galen’s These instances are given, however, without prejudice to the system of generalisation and deduction which, in Galen’s hands, often proved exceedingly fruitful. He is said to have tried “to unite professional and scientific medicine with a philosophic link.” He objected, however, to such extreme attempts at simplification of medical science as that of the Methodists, to whom diseases were isolated entities, without any relationships in time or space (v. p. xv. supra). He based much of his pathological reasoning upon Pg xxxiii the “humoral theory” of Hippocrates, according to which certain diseases were caused by one or more of the four humours (blood, phlegm, black and yellow bile) being in excess—that is, by various dyscrasiae. Our modern conception of “hormone” action shows certain resemblances with this theory. Besides observation and reasoning, Galen took his stand on experiment; he was one of the first of experimental physiologists, as is illustrated in the present book by his researches into the function of the kidneys (p. 59 et seq.). He also conducted a long series of experiments into the physiology of the spinal cord, to determine what parts controlled movement and what sensibility. As a practitioner he modelled his work largely on the broad and simple lines laid down by Hippocrates. He had also at his disposal all the acquisitions of biological science dating from the time of Aristotle five hundred years earlier, and reinforced by the discoveries in anatomy made by the Alexandrian school. To these he added a large series of researches of his own. Galen never confined himself to what one might call the academic or strictly orthodox sources of information; he roamed the world over for answers to his queries. For example, we find him on his journeys between Pergamos and Rome twice visiting the island of Lemnos in order to procure some of the terra sigillata, a kind of earth which had a reputation for healing the bites of serpents and Pg xxxiv other wounds. At other times he visited the copper-mines of Cyprus in search for copper, and Palestine for the resin called Balm of Gilead. By inclination and training Galen was the reverse of a “party-man.” In the Natural Faculties (p. 55) he speaks of the bane of sectarian partizanship, “harder to heal than any itch.” He pours scorn upon the ignorant “Erasistrateans” and “Asclepiadeans,” who attempted to hide their own incompetence under the shield of some great man’s name (cf. p. 141). Of the two chief objects of his censure in the Natural Faculties, Galen deals perhaps less rigorously with Erasistratus than with Asclepiades. Erasistratus did at least recognize the existence of a vital principle in the organism, albeit, with his eye on the structures which the scalpel displayed he tended frequently to forget it. The researches of the anatomical school of Alexandria had been naturally of the greatest service to surgery, but in medicine they sometimes had a tendency to check progress by diverting attention from the whole to the part. The This view of a “vital principle” as necessarily consisting of matter in a finely divided, fluid, or “etheric” state is not unknown even in our day. Belief in the fundamental importance of the Pneuma formed the basis of the teaching of another vitalist school in ancient Greece, that of the Pneumatists. Galen and Galen’s Readers of the following pages will notice that Galen uses what we should call distinctly immoderate language towards those who ventured to differ from the views of his master Hippocrates (which were also his own). The employment of such language was one of the few weaknesses of his age which he did not transcend. Possibly also his mother’s choleric temper may have predisposed him to it. The fact, too, that his vivisection experiments (e.g. pp. 59, 273) were carried out apparently without any kind of anaesthetisation being even thought of is abhorrent to the feelings of to-day, but must be excused also on the ground that callousness towards animals was then customary, men having probably never thought much about the subject. Galen’s Readers will be surprised to find how many words are used by Galen which they would have thought had been expressly coined to fit modern conceptions; thus our author employs not merely such terms as physiology, phthisis, atrophy, anastomosis, but also haematopoietic, anaesthesia, and even aseptic! It is only fair, however, to remark that these terms, particularly the last, were not used by Galen in quite their modern significance. Summary. To resume, then: What contribution can Galen bring to the art of healing at the present day? It was not, surely, for nothing that the great Pergamene gave laws to the medical world for over a thousand years! Let us draw attention once more to: (1) The high ideal which he set before the profession. (2) His insistence on immediate contact with nature as the primary condition for arriving at an understanding of disease; on the need for due consideration of previous authorities; on the need also for reflection—for employment of the mind’s eye (ἡ λογικὴ θεωρία) as an aid to the physical eye. (3) His essentially broad outlook, which often helped him in the comprehension of a phenomenon through his knowledge of an analogous phenomenon in another field of nature. (4) His keen appreciation of the unity of the organism, and of the inter-dependence of its parts; his realisation that the vital phenomena (physiological and pathological) in a living organism can only be understood when considered in relation to the environment of that organism or part. This is the foundation for the war that Galen waged À outrance on the Methodists, to whom diseases were things without relation to anything. This dispute is, unfortunately, not touched upon in the present volume. What Galen combated was the tendency, familiar enough in our own day, to reduce medicine to the science of finding a label for each patient, and then treating not the patient, but the label. (This tendency, we may remark in parenthesis, is one which is obviously well suited for the standardising purposes of a State medical service, and is therefore one which all who have the weal of the profession at heart must most jealously watch in the difficult days that lie ahead.) (5) His realisation of the inappropriateness and inadequacy of physical formulae in explaining physiological activities. Galen’s disputes with Asclepiades over τὰ πρῶτα ἐκεῖνα σώματα τὰ ἀπαθῆ, over the ἄναρμα στοιχεῖα καὶ ληρώδεις ὄγκοι, is but another aspect of his quarrel with the Methodists regarding their pathological “units,” whose primary characteristic was just this same ἀπάθεια (impassiveness to environment, “unimpressionability”). We have of course Pg xl our Physiatric or Iatromechanical school at the present day, to whom such processes as absorption from the alimentary canal, the respiratory interchange of gases, and the action of the renal epithelium are susceptible of a purely physical explanation.4 (6) His quarrel with the Anatomists, which was in essence the same as that with the Atomists, and which arose from his clear realisation that that primary and indispensable desideratum, a view of the whole, could never be obtained by a mere summation of partial views; hence, also, his sense of the dangers which would beset the medical art if it were allowed to fall into the hands of a mere crowd of competing specialists without any organising head to guide them. |